The destruction of mucosal barriers, epithelial remodeling, and impaired mucociliary clearance: possible pathogenic mechanisms of Pseudomonas aeruginosa and Staphylococcus aureus in chronic rhinosinusitis

The destruction of mucosal barriers, epithelial remodeling, and impaired mucociliary clearance: possible pathogenic mechanisms of Pseudomonas aeruginosa and Staphylococcus aureus in chronic rhinosinusitis

Abstract Chronic rhinosinusitis (CRS) is a pathological condition characterized by persistent inflammation in the upper respiratory tract and paranasal sinuses. The epithelium serves as the first line of defense against potential threats and protects the nasal mucosa. The fundamental mechanical barr...

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Bibliographic Details
Main Authors: Zahra Chegini, Milad Noei, Jaber Hemmati, Mohammad Reza Arabestani, Aref Shariati
Format: Article
Language:English
Published: BMC 2023-10-01
Series:Cell Communication and Signaling
Subjects:
CRS
Staphylococcus aureous
Pseudomonas aeruginosa
Mucociliary clearance
Epithelial remodeling
Mucosal barriers
Online Access:https://doi.org/10.1186/s12964-023-01347-2

Internet

https://doi.org/10.1186/s12964-023-01347-2

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