Leptin receptor deficiency impedes metabolic surgery related-weight loss through inhibition of energy expenditure in db/db mice

Leptin receptor deficiency impedes metabolic surgery related-weight loss through inhibition of energy expenditure in db/db mice

Abstract Background Roux-en-Y gastric bypass (RYGB) surgery is an effective metabolic surgery against diabetes and obesity. Clinical evidence indicates that patients with severe obesity have a poor curative effect in losing weight if they suffer from leptin or its receptor deficiency, but the underl...

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Bibliographic Details
Main Authors: Dan Tong, Jie Xiang, Wei Liu, Fang Sun, Lijuan Wang, Aidi Mou, Tingbing Cao, Qing Zhou, Mei You, Yingying Liao, Peng Gao, Daoyan Liu, Zongshi Lu, Zhiming Zhu
Format: Article
Language:English
Published: BMC 2024-02-01
Series:Diabetology & Metabolic Syndrome
Subjects:
Roux-en-Y gastric bypass
Leptin receptor
Weight regain
AMPK
Online Access:https://doi.org/10.1186/s13098-024-01270-7

Internet

https://doi.org/10.1186/s13098-024-01270-7

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