Mouse germ line mutations due to retrotransposon insertions

Mouse germ line mutations due to retrotransposon insertions

Abstract Transposable element (TE) insertions are responsible for a significant fraction of spontaneous germ line mutations reported in inbred mouse strains. This major contribution of TEs to the mutational landscape in mouse contrasts with the situation in human, where their relative contribution a...

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Bibliographic Details
Main Authors: Liane Gagnier, Victoria P. Belancio, Dixie L. Mager
Format: Article
Language:English
Published: BMC 2019-04-01
Series:Mobile DNA
Subjects:
Endogenous retroviruses
Long terminal repeats
Long interspersed elements
Short interspersed elements
Germ line mutation
Inbred mice
Online Access:http://link.springer.com/article/10.1186/s13100-019-0157-4

Internet

http://link.springer.com/article/10.1186/s13100-019-0157-4

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