FK506 increases susceptibility to musculoskeletal infection in a rodent model
Abstract Background Delayed fracture healing caused by soft tissue loss can be resolved by the administration of a Th1 immunosuppressant, such as FK506. Additionally, open fractures are at high risk for infection. We hypothesized that the inclusion of an immunosuppressant to a subject at risk for a...
Main Authors: | Stefanie M. Shiels, Preeti J. Muire, Joseph C. Wenke |
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Format: | Article |
Language: | English |
Published: |
BMC
2022-07-01
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Series: | BMC Musculoskeletal Disorders |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12891-022-05667-1 |
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