Obeticholic acid treatment ameliorates the cardiac dysfunction in NASH mice

Obeticholic acid treatment ameliorates the cardiac dysfunction in NASH mice

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<h4>Background</h4> Suppression of cardiac iinflammasome, which can be inhibited by Farnesoid X receptor (FXR) agonist, can ameliorate cardiac inflammation and fibrosis. Increased cardiac inflammasome decrease the abundance of regulatory T (Treg) cells and exacerbate cardiac dysfunction....

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Bibliographic Details
Main Authors: Szu-Yu Liu, Chia-Chang Huang, Ying-Ying Yang, Shiang-Fen Huang, Tzung-Yan Lee, Tzu-Hao Li, Ming-Chih Hou, Han-Chieh Lin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9733885/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9733885/?tool=EBI

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