Causality between Ankylosing Spondylitis and osteoarthritis in European ancestry: a bidirectional Mendelian randomization study

Causality between Ankylosing Spondylitis and osteoarthritis in European ancestry: a bidirectional Mendelian randomization study

ObjectiveTo explore the bidirectional causal relationship between Ankylosing Spondylitis (AS) and Osteoarthritis (OA) at the genetic level within the European ancestry.MethodsWe implemented a series of quality control steps to select instrumental variables (IVs) related to the exposure. We conducted...

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Bibliographic Details
Main Authors: Yangguang Lu, Di Lu, Hongzhi Zhang, Haoyang Li, Bohuai Yu, Yige Zhang, Hantao Hu, Hongfeng Sheng
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-02-01
Series:Frontiers in Immunology
Subjects:
Ankylosing Spondylitis
osteoarthritis
Mendelian randomization
genetic analyses
orthopedics
inflammation
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1297454/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2024.1297454/full

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