Real-Time Monitoring of Levetiracetam Effect on the Electrophysiology of an Heterogenous Human iPSC-Derived Neuronal Cell Culture Using Microelectrode Array Technology

Real-Time Monitoring of Levetiracetam Effect on the Electrophysiology of an Heterogenous Human iPSC-Derived Neuronal Cell Culture Using Microelectrode Array Technology

Levetiracetam (LEV) is a broad-spectrum and widely used antiepileptic drug that also has neuroprotective effects in different neurological conditions. Given its complex interaction with neuronal physiology, a better comprehension of LEV effects on neurons activity is needed. Microelectrode arrays (M...

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Bibliographic Details
Main Authors: Andrea Di Credico, Giulia Gaggi, Pascal Izzicupo, Laura Ferri, Laura Bonanni, Giovanni Iannetti, Angela Di Baldassarre, Barbara Ghinassi
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Biosensors
Subjects:
microelectrode array
biosensors
real-time monitoring
iPSC-derived neurons
drug screening
Levetiracetam
Online Access:https://www.mdpi.com/2079-6374/11/11/450

Internet

https://www.mdpi.com/2079-6374/11/11/450

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