Androgen-regulated MafB drives cell migration via MMP11-dependent extracellular matrix remodeling in mice

Summary: While androgen is considered a pivotal regulator of sexually dimorphic development, it remains unclear how it orchestrates the differentiation of reproductive organs. Using external genitalia development as a model, we showed that androgen, through the transcription factor MafB, induced cel...

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Bibliographic Details
Main Authors: Mellissa C. Alcantara, Kentaro Suzuki, Alvin R. Acebedo, Daiki Kajioka, Satoshi Hirohata, Tsuneyasu Kaisho, Yu Hatano, Kazuo Yamagata, Satoru Takahashi, Gen Yamada
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004222018818