Surface TREM2 on circulating M-MDSCs as a novel prognostic factor for adults with treatment-naïve diffuse large B-cell lymphoma

Surface TREM2 on circulating M-MDSCs as a novel prognostic factor for adults with treatment-naïve diffuse large B-cell lymphoma

Abstract Introduction Circulating monocytic myeloid-derived suppressive cells (M-MDSCs) are implicated as a poor prognostic factor and cause CAR T-cell failure in diffuse large B-cell lymphoma (DLBCL). Triggering receptors expressed on myeloid cells 2 (TREM2) are a transmembrane glycoprotein that po...

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Bibliographic Details
Main Authors: Hao-Yuan Wang, Fu-Chen Yang, Ching-Fen Yang, Yao-Chung Liu, Po-Shen Ko, Chien-Jung Li, Chun-Kuang Tsai, Yi-Lin Chung, Nien-Jung Chen
Format: Article
Language:English
Published: BMC 2023-04-01
Series:Experimental Hematology & Oncology
Subjects:
Arginase 1
Cytotoxic T lymphocytes (CTLs)
Diffuse large B-cell lymphoma (DLBCL)
Monocytic myeloid-derived suppressor cells (M-MDSCs)
Triggering receptors expressed on myeloid cells 2 (TREM2)
Online Access:https://doi.org/10.1186/s40164-023-00399-x

Internet

https://doi.org/10.1186/s40164-023-00399-x

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