Fc gamma receptor IIb in tumor-associated macrophages and dendritic cells drives poor prognosis of recurrent glioblastoma through immune-associated signaling pathways

Fc gamma receptor IIb in tumor-associated macrophages and dendritic cells drives poor prognosis of recurrent glioblastoma through immune-associated signaling pathways

Background: Among central nervous system tumors, glioblastoma (GBM) is considered to be the most destructive malignancy. Recurrence is one of the most fatal aspects of GBM. However, the driver molecules that trigger GBM recurrence are currently unclear.Methods: The mRNA expression data and clinical...

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Bibliographic Details
Main Authors: Xiong Jin, Jianlei Kang, Qing Lu, Shuang-Lei Guo, Meichen Liu, Yue Zhang, Can Cui, Hong-Lin Liu, Xin Xu, Jinlong Yin
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Genetics
Subjects:
recurrent glioblastoma
Fcgr2b
tumor-associated macrophage
dendritic cell
immune-associated signaling pathway
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2022.1046008/full

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https://www.frontiersin.org/articles/10.3389/fgene.2022.1046008/full

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