Does a subset of mature T‐cell leukemias with features akin to T‐cell prolymphocytic leukemia but lacking rearrangement of the TCL1 represent peripheral T‐cell lymphoma, NOS in a leukemic phase?

Abstract In the current WHO classification, a T‐cell prolymphocytic leukemia (T‐PLL) diagnosis requires lymphocytosis of >5 × 109/L, evidence of monoclonality, and TCL1A or MTCP1 rearrangement. However, the 2019 consensus document suggested that in the absence of rearrangement of TCL1‐family, the...

Full description

Bibliographic Details
Main Authors: David C. Gajzer, Xueyan Chen, Daniel E. Sabath, Christina Poh, Kikkeri N. Naresh
Format: Article
Language:English
Published: Wiley 2024-08-01
Series:eJHaem
Online Access:https://doi.org/10.1002/jha2.953