In silico studies, X-ray diffraction analysis and biological investigation of fluorinated pyrrolylated-chalcones in zebrafish epilepsy models

In silico studies, X-ray diffraction analysis and biological investigation of fluorinated pyrrolylated-chalcones in zebrafish epilepsy models

Epilepsy is the third most common known brain disease worldwide. Several antiepileptic drugs (AEDs) are available to improve seizure control. However, the associated side effects limit their practical use and highlight the ongoing search for safer and effective AEDs. Eighteen newly designed fluorine...

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Bibliographic Details
Main Authors: Muhammad Syafiq Akmal Mohd Fahmi, Puspanjali Swain, Amirah Hani Ramli, Wan Norhamidah Wan Ibrahim, Nur Atikah Saleh Hodin, Noraini Abu Bakar, Yee Seng Tan, Siti Munirah Mohd Faudzi, Cheol-Hee Kim
Format: Article
Language:English
Published: Elsevier 2023-02-01
Series:Heliyon
Subjects:
Chalcones
Antiepileptic drugs (AEDs)
Zebrafish
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844023008927

Internet

http://www.sciencedirect.com/science/article/pii/S2405844023008927

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