Phosphatidic acid regulation of PIPKI is critical for actin cytoskeletal reorganization[S]

Type I phosphatidylinositol-4-phosphate 5-kinase (PIPKI) is the main enzyme generating the lipid second messenger phosphatidylinositol-4,5-bisphosphate [PI(4,5)P2], which has critical functions in many cellular processes, such as cytoskeletal reorganization, membrane trafficking, and signal transduc...

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Bibliographic Details
Main Authors: Akua N. Roach, Ziqing Wang, Ping Wu, Feng Zhang, Robin B. Chan, Yoshiya Yonekubo, Gilbert Di Paolo, Alemayehu A. Gorfe, Guangwei Du
Format: Article
Language:English
Published: Elsevier 2012-12-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S002222752041795X