Elucidation of Focal Adhesion Kinase as a Modulator of Migration and Invasion and as a Potential Therapeutic Target in Chronic Lymphocytic Leukemia

Elucidation of Focal Adhesion Kinase as a Modulator of Migration and Invasion and as a Potential Therapeutic Target in Chronic Lymphocytic Leukemia

The retention and re-migration of Chronic Lymphocytic Leukemia cells into cytoprotective and proliferative lymphoid niches is thought to contribute to the development of resistance, leading to subsequent disease relapse. The aim of this study was to elucidate the molecular processes that govern CLL...

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Bibliographic Details
Main Authors: Thomas A. Burley, Andrew Hesketh, Giselda Bucca, Emma Kennedy, Eleni E. Ladikou, Benjamin P. Towler, Simon Mitchell, Colin P. Smith, Christopher Fegan, Rosalynd Johnston, Andrea Pepper, Chris Pepper
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Cancers
Subjects:
chronic lymphocytic leukemia
FAK
TLR9
migration
transcriptomics
miRNomics
Online Access:https://www.mdpi.com/2072-6694/14/7/1600

Internet

https://www.mdpi.com/2072-6694/14/7/1600

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