Natural and Tumor Induced Regulatory T-cells in Malignant Glioma
One of the hallmark features of glioblastoma multiforme (GBM), the most common adult primary brain tumor with a very dismal prognosis, is the accumulation of CD4+CD25+Foxp3+ regulatory T cells (Tregs). Regulatory T cells (Tregs) segregate into two primary categories: thymus-derived natural Tregs (nT...
| Auteur principal: | |
|---|---|
| Format: | Article |
| Langue: | English |
| Publié: |
Frontiers Media S.A.
2013-05-01
|
| Collection: | Frontiers in Immunology |
| Sujets: | |
| Accès en ligne: | http://journal.frontiersin.org/Journal/10.3389/fimmu.2013.00116/full |