Impaired Antibody-Independent Immune Response of B Cells in Patients With Acute Dengue Infection

Impaired Antibody-Independent Immune Response of B Cells in Patients With Acute Dengue Infection

Dengue is a mosquito-borne viral disease caused by dengue virus (DENV). The disease is endemic to more than 100 countries with 390 million dengue infections per year. Humoral immune responses during primary and secondary DENV infections are well-investigated. However, the impact of DENV infection on...

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Bibliographic Details
Main Authors: Vinit Upasani, Hoa Thi My Vo, Sivlin Ung, Sothy Heng, Denis Laurent, Rithy Choeung, Veasna Duong, Sopheak Sorn, Sowath Ly, Izabela A. Rodenhuis-Zybert, Philippe Dussart, Tineke Cantaert
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-10-01
Series:Frontiers in Immunology
Subjects:
dengue virus
regulatory B cells (Bregs)
immunopathogenesis of dengue
plasmacells
IL-10
B cell subsets
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.02500/full

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https://www.frontiersin.org/article/10.3389/fimmu.2019.02500/full

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