Mechanism and consequences of herpes simplex virus 1-mediated regulation of host mRNA alternative polyadenylation.

Mechanism and consequences of herpes simplex virus 1-mediated regulation of host mRNA alternative polyadenylation.

Eukaryotic gene expression is extensively regulated by cellular stress and pathogen infections. We have previously shown that herpes simplex virus 1 (HSV-1) and several cellular stresses cause widespread disruption of transcription termination (DoTT) of RNA polymerase II (RNAPII) in host genes and t...

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Main Authors: Xiuye Wang, Liang Liu, Adam W Whisnant, Thomas Hennig, Lara Djakovic, Nabila Haque, Cindy Bach, Rozanne M Sandri-Goldin, Florian Erhard, Caroline C Friedel, Lars Dölken, Yongsheng Shi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-03-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1009263

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https://doi.org/10.1371/journal.pgen.1009263

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