Phlorofucofuroeckol-A refined by edible brown algae Ecklonia cava indicates anti-inflammatory effects on TNF-α/IFN-γ-stimulated HaCaT keratinocytes and 12-O-tetradecanoylphorbol 13-acetate-induced ear edema in BALB/c mice

Phlorofucofuroeckol-A refined by edible brown algae Ecklonia cava indicates anti-inflammatory effects on TNF-α/IFN-γ-stimulated HaCaT keratinocytes and 12-O-tetradecanoylphorbol 13-acetate-induced ear edema in BALB/c mice

The present study investigated the anti-inflammatory potential of phlorofucofuroeckol-A (PFF-A) from Ecklonia cava in TNF-α/IFN-γ-stimulated HaCaT keratinocytes and an acute ear edema mice model. Upon investigation, PFF-A had no cytotoxicity up to 62.5 μg/mL and indicated a dose-dependent-cytoprotec...

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Bibliographic Details
Main Authors: Kirinde Gedara Isuru Sandanuwan Kirindage, Arachchige Maheshika Kumari Jayasinghe, Eui-Jeong Han, Hee-Jin Han, Kil-Nam Kim, Lei Wang, Soo-Jin Heo, Kyung-Sook Jung, Ginnae Ahn
Format: Article
Language:English
Published: Elsevier 2023-10-01
Series:Journal of Functional Foods
Subjects:
Echlonia cava
Phlorofucofuroeckol-A
Anti-inflammation
HaCaT keratinocytes
Acute ear edema
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464623003869

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http://www.sciencedirect.com/science/article/pii/S1756464623003869

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