Contribution of Mesenteric Lymph Nodes and GALT to the Intestinal Foxp3+ Regulatory T-Cell CompartmentSummary

Background & Aims: Foxp3+ regulatory T cells (Tregs) in the intestine promote immune tolerance to enteric antigens. Previous studies have shown that C-C chemokine receptor 7 (CCR7)-dependent migration of intestinal dendritic cells to the mesenteric lymph nodes (mLN) is involved in peripheral Fox...

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Bibliographic Details
Main Authors: Duke Geem, Vu Ngo, Akihito Harusato, Benoit Chassaing, Andrew T. Gewirtz, Rodney D. Newberry, Timothy L. Denning
Format: Article
Language:English
Published: Elsevier 2016-05-01
Series:Cellular and Molecular Gastroenterology and Hepatology
Online Access:http://www.sciencedirect.com/science/article/pii/S2352345X16000060