<sup>99m</sup>Tc-Labeled Cyclic Peptide Targeting PD-L1 as a Novel Nuclear Imaging Probe

<sup>99m</sup>Tc-Labeled Cyclic Peptide Targeting PD-L1 as a Novel Nuclear Imaging Probe

Recent cancer therapies have focused on reducing immune suppression in the tumor microenvironment to prevent cancer progression and metastasis. PD-1 is a checkpoint protein that stops the immune response and is expressed on immune T cells. Cancer cells express a PD-1 ligand (PD-L1) to bind to the T-...

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Bibliographic Details
Main Authors: Guillermina Ferro-Flores, Blanca Ocampo-García, Pedro Cruz-Nova, Myrna Luna-Gutiérrez, Gerardo Bravo-Villegas, Erika Azorín-Vega, Nallely Jiménez-Mancilla, Emiliano Michel-Sánchez, Osvaldo García-Pérez, Nancy Lara-Almazán, Clara Santos-Cuevas
Format: Article
Language:English
Published: MDPI AG 2023-11-01
Series:Pharmaceutics
Subjects:
PD-L1
technetium-99m
PD-L1 peptide inhibitor
SPECT
PD-L1 imaging
Online Access:https://www.mdpi.com/1999-4923/15/12/2662

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https://www.mdpi.com/1999-4923/15/12/2662

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