Profound human/mouse differences in alpha-dystrobrevin isoforms: a novel syntrophin-binding site and promoter missing in mouse and rat

<p>Abstract</p> <p>Background</p> <p>The dystrophin glycoprotein complex is disrupted in Duchenne muscular dystrophy and many other neuromuscular diseases. The principal heterodimeric partner of dystrophin at the heart of the dystrophin glycoprotein complex in the main...

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Bibliographic Details
Main Authors: Jin Hong, Tan Sipin, Constantinou Panayiotis, Böhm Sabrina V, Roberts Roland G
Format: Article
Language:English
Published: BMC 2009-12-01
Series:BMC Biology
Online Access:http://www.biomedcentral.com/1741-7007/7/85