Tsc2 coordinates neuroprogenitor differentiation

Summary: Neural stem cells (NSCs) of the ventricular-subventricular zone (V-SVZ) generate numerous cell types. The uncoupling of mRNA transcript availability and translation occurs during the progression from stem to differentiated states. The mTORC1 kinase pathway acutely controls proteins that reg...

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Bibliographic Details
Main Authors: Victoria A. Riley, Vijay Shankar, Jennie C. Holmberg, Aidan M. Sokolov, Victoria N. Neckles, Kaitlyn Williams, Rachel Lyman, Trudy F.C. Mackay, David M. Feliciano
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223025191