Urea Gel Electrophoresis in Studies of Conformational Changes of Transferrin on Binding and Transport of Non-Ferric Metal Ions

Transferrin (Tf) is a crucial transporter protein for Fe(III), but its biological role in binding other metal ions and their delivery into cells remain highly controversial. The first systematic exploration of the effect of non-Fe(III) metal ion binding on Tf conformation has been performed by urea-...

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Bibliographic Details
Main Authors: Aviva Levina, Boer Wang, Peter A. Lay
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Gels
Subjects:
Online Access:https://www.mdpi.com/2310-2861/8/1/19