The effects of resuscitation with different plasma products on endothelial permeability and organ injury in a rat pneumosepsis model

Abstract Background Endothelial injury and permeability are a hallmark of sepsis. Initial resuscitation of septic patients with crystalloids is associated with aggravation of endothelial permeability, which may be related either to low protein content or to volume. We investigated whether initial re...

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Bibliographic Details
Main Authors: Daan P. van den Brink, Derek J. B. Kleinveld, Annabel Bongers, Jaël Vos, Joris J. T. H. Roelofs, Nina C. Weber, Jaap D. van Buul, Nicole P. Juffermans
Format: Article
Language:English
Published: SpringerOpen 2023-09-01
Series:Intensive Care Medicine Experimental
Subjects:
Online Access:https://doi.org/10.1186/s40635-023-00549-9