Comparison of the GPVI inhibitors losartan and honokiol

Comparison of the GPVI inhibitors losartan and honokiol

Losartan and honokiol are small molecules which have been described to inhibit aggregation of platelets by collagen. Losartan has been proposed to block clustering of GPVI but not to affect binding of collagen. Honokiol has been reported to bind directly to GPVI but only at a concentration that is t...

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Bibliographic Details
Main Authors: Marie-Blanche Onselaer, Magdolna Nagy, Chiara Pallini, Jeremy A Pike, Gina Perrella, Lourdes Garcia Quintanilla, Johannes A Eble, Natalie S. Poulter, Johan W.M. Heemskerk, Steve P Watson
Format: Article
Language:English
Published: Taylor & Francis Group 2020-02-01
Series:Platelets
Subjects:
clec-2
gpvi
honokiol
losartan
platelets
Online Access:http://dx.doi.org/10.1080/09537104.2019.1585526

Internet

http://dx.doi.org/10.1080/09537104.2019.1585526

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