miR‐10b*, a master inhibitor of the cell cycle, is down‐regulated in human breast tumours

miR‐10b*, a master inhibitor of the cell cycle, is down‐regulated in human breast tumours

Abstract Deregulated proliferation is a hallmark of cancer cells. Here, we show that microRNA‐10b* is a master regulator of breast cancer cell proliferation and is downregulated in tumoural samples versus matched peritumoural counterparts. Two canonical CpG islands (5 kb) upstream from the precursor...

Full description

Bibliographic Details
Main Authors: Francesca Biagioni, Noa Bossel Ben‐Moshe, Giulia Fontemaggi, Valeria Canu, Federica Mori, Barbara Antoniani, Anna Di Benedetto, Raffaela Santoro, Sabrina Germoni, Fernanda De Angelis, Anna Cambria, Roi Avraham, Giuseppe Grasso, Sabrina Strano, Paola Muti, Marcella Mottolese, Yosef Yarden, Eytan Domany, Giovanni Blandino
Format: Article
Language:English
Published: Springer Nature 2012-11-01
Series:EMBO Molecular Medicine
Subjects:
breast cancer
cell proliferation
expression profiling
microRNA
miR‐10b*
Online Access:https://doi.org/10.1002/emmm.201201483

Internet

https://doi.org/10.1002/emmm.201201483

Similar Items