Changes in dynamics upon oligomerization regulate substrate binding and allostery in amino acid kinase family members.

Changes in dynamics upon oligomerization regulate substrate binding and allostery in amino acid kinase family members.

Oligomerization is a functional requirement for many proteins. The interfacial interactions and the overall packing geometry of the individual monomers are viewed as important determinants of the thermodynamic stability and allosteric regulation of oligomers. The present study focuses on the role of...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς:	Enrique Marcos, Ramon Crehuet, Ivet Bahar
Μορφή:	Άρθρο
Γλώσσα:	English
Έκδοση:	Public Library of Science (PLoS) 2011-09-01
Σειρά:	PLoS Computational Biology
Διαθέσιμο Online:	http://europepmc.org/articles/PMC3182869?pdf=render

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