Changes in dynamics upon oligomerization regulate substrate binding and allostery in amino acid kinase family members.

Changes in dynamics upon oligomerization regulate substrate binding and allostery in amino acid kinase family members.

Oligomerization is a functional requirement for many proteins. The interfacial interactions and the overall packing geometry of the individual monomers are viewed as important determinants of the thermodynamic stability and allosteric regulation of oligomers. The present study focuses on the role of...

書誌詳細
主要な著者:	Enrique Marcos, Ramon Crehuet, Ivet Bahar
フォーマット:	論文
言語:	English
出版事項:	Public Library of Science (PLoS) 2011-09-01
シリーズ:	PLoS Computational Biology
オンライン･アクセス:	http://europepmc.org/articles/PMC3182869?pdf=render

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