Changes in dynamics upon oligomerization regulate substrate binding and allostery in amino acid kinase family members.

Changes in dynamics upon oligomerization regulate substrate binding and allostery in amino acid kinase family members.

Oligomerization is a functional requirement for many proteins. The interfacial interactions and the overall packing geometry of the individual monomers are viewed as important determinants of the thermodynamic stability and allosteric regulation of oligomers. The present study focuses on the role of...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид:	Enrique Marcos, Ramon Crehuet, Ivet Bahar
Формат:	Өгүүллэг
Хэл сонгох:	English
Хэвлэсэн:	Public Library of Science (PLoS) 2011-09-01
Цуврал:	PLoS Computational Biology
Онлайн хандалт:	http://europepmc.org/articles/PMC3182869?pdf=render

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