Dysregulated myokines and signaling pathways in skeletal muscle dysfunction in a cigarette smoke–induced model of chronic obstructive pulmonary disease

Dysregulated myokines and signaling pathways in skeletal muscle dysfunction in a cigarette smoke–induced model of chronic obstructive pulmonary disease

Skeletal muscle dysfunction is an important extrapulmonary comorbidity of chronic obstructive pulmonary disease (COPD). Muscle-derived cytokines (myokines) play important roles in skeletal muscle growth and function, but their contributions to skeletal muscle dysfunction in COPD have not been fully...

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Bibliographic Details
Main Authors: Lijiao Zhang, Chunxiao Li, Jing Xiong, Chun Chang, Yongchang Sun
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Physiology
Subjects:
chronic obstructive pulmonary disease (COPD)
cigarette smoke
FNDC5/irisin
myostatin
ERK
skeletal muscle dysfunction
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2022.929926/full

Internet

https://www.frontiersin.org/articles/10.3389/fphys.2022.929926/full

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