Proteases: essential actors in processing antigens and intracellular Toll-like receptors
MHC class II molecules expressed by professional antigen presenting cells (pAPCs) such as macrophages, B cells and dendritic cells (DCs) play a fundamental role in presenting peptides to CD4+ T cells. However, to elicit CD4+-T cells immunity, pAPCs need an additional signal, which can be delivered b...
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Format: | Article |
Language: | English |
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Frontiers Media S.A.
2013-09-01
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Series: | Frontiers in Immunology |
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Online Access: | http://journal.frontiersin.org/Journal/10.3389/fimmu.2013.00299/full |