Proteases: essential actors in processing antigens and intracellular Toll-like receptors

Proteases: essential actors in processing antigens and intracellular Toll-like receptors

MHC class II molecules expressed by professional antigen presenting cells (pAPCs) such as macrophages, B cells and dendritic cells (DCs) play a fundamental role in presenting peptides to CD4+ T cells. However, to elicit CD4+-T cells immunity, pAPCs need an additional signal, which can be delivered b...

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Bibliographic Details
Main Author: Bénédicte eManoury
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-09-01
Series:Frontiers in Immunology
Subjects:
Dendritic Cells
processing
antigen processing
Proteases
MHC class II
invariant chain
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2013.00299/full

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