Effect of oral zinc regimens on human hepatic copper content: a randomized intervention study

Abstract Zinc inhibits intestinal copper uptake, an effect utilized for treating Wilson’s disease (WD). We used copper-64 (64Cu) PET/CT to examine how much four weeks of treatment with different zinc regimens reduced the hepatic 64Cu content after oral 64Cu administration and test if alternative reg...

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Bibliographic Details
Main Authors: Ditte Emilie Munk, Tea Lund Laursen, Frederik Teicher Kirk, Hendrik Vilstrup, Aftab Ala, Lars Christian Gormsen, Peter Ott, Thomas Damgaard Sandahl
Format: Article
Language:English
Published: Nature Portfolio 2022-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-18872-8