Renal expression of FGF23 in progressive renal disease of diabetes and the effect of ACE inhibitor.

Fibroblast growth factor 23 (FGF23) is a phosphaturic hormone mainly produced by bone that acts in the kidney through FGF receptors and Klotho. Here we investigated whether the kidney was an additional source of FGF23 during renal disease using a model of type 2 diabetic nephropathy. Renal expressio...

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Bibliographic Details
Main Authors: Cristina Zanchi, Monica Locatelli, Ariela Benigni, Daniela Corna, Susanna Tomasoni, Daniela Rottoli, Flavio Gaspari, Giuseppe Remuzzi, Carlamaria Zoja
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3743899?pdf=render