Decreased plasma levels of PDGF-BB, VEGF-A, and HIF-2α in preterm infants after ibuprofen treatment

Decreased plasma levels of PDGF-BB, VEGF-A, and HIF-2α in preterm infants after ibuprofen treatment

IntroductionIbuprofen is one of the most common non-steroidal anti-inflammatory drugs used to close patent ductus arteriosus (PDA) in preterm infants. PDA is associated with bronchopulmonary dysplasia (BPD), while PDA closure by ibuprofen did not reduce the incidence of BPD or death. Previous studie...

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Bibliographic Details
Main Authors: Xuemei Huang, Dongshan Han, Yanfei Wei, Bingchun Lin, Dingyuan Zeng, Yu Zhang, Ba Wei, Zhifeng Huang, Xueyu Chen, Chuanzhong Yang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Pediatrics
Subjects:
patent ductus arteriosus
angiogenesis
growth factors
hsPDA
bronchopulmonary dysplasia (BPD)
ibuprofen
Online Access:https://www.frontiersin.org/articles/10.3389/fped.2022.919879/full

Internet

https://www.frontiersin.org/articles/10.3389/fped.2022.919879/full

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