Targeting TCTP sensitizes tumor to T cell-mediated therapy by reversing immune-refractory phenotypes
Translationally controlled tumor protein (TCTP) regulates several cellular processes, including apoptosis, and is overexpressed in several cancer types. Here, the authors report that high levels of TCTP are associated with poor response to anti-PD-L1 and that TCTP targeting increases the efficacy of...
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Bibliographic Details
| Main Authors: |
Hyo-Jung Lee,
Kwon-Ho Song,
Se Jin Oh,
Suyeon Kim,
Eunho Cho,
Jungwon Kim,
Yun gyu Park,
Kyung-Mi Lee,
Cassian Yee,
Seung-Hwa Song,
Suhwan Chang,
Jungmin Choi,
Sang Taek Jung,
Tae Woo Kim |
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| Format: | Article
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| Language: | English |
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| Published: |
Nature Portfolio
2022-04-01
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| Series: | Nature Communications
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| Online Access: | https://doi.org/10.1038/s41467-022-29611-y
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