Overexpressed NEDD8 as a potential therapeutic target in esophageal squamous cell carcinoma

Overexpressed NEDD8 as a potential therapeutic target in esophageal squamous cell carcinoma

Objective: The hyperactivated neddylation pathway plays an important role in tumorigenesis and is emerging as a promising anticancer target. We aimed to study whether NEDD8 (neural precursor cell expressed, developmentally down-regulated 8) might serve as a therapeutic target in esophageal squamous...

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Bibliographic Details
Main Authors: Jingrong Xian, Shiwen Wang, Yanyu Jiang, Lihui Li, Lili Cai, Ping Chen, Yue Liu, Xiaofei Zeng, Guoan Chen, Chen Ding, Robert M. Hoffman, Lijun Jia, Hu Zhao, Yanmei Zhang
Format: Article
Language:English
Published: China Anti-Cancer Association 2022-04-01
Series:Cancer Biology & Medicine
Subjects:
snedd8
esophageal squamous cell carcinoma
cullin-ring e3 ubiquitin ligases
apoptosis
anticancer target
Online Access:https://www.cancerbiomed.org/content/19/4/504

Internet

https://www.cancerbiomed.org/content/19/4/504

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