Elevated NF-κB/SHh/GLI1 Signature Denotes a Worse Prognosis and Represent a Novel Potential Therapeutic Target in Advanced Prostate Cancer

Elevated NF-κB/SHh/GLI1 Signature Denotes a Worse Prognosis and Represent a Novel Potential Therapeutic Target in Advanced Prostate Cancer

Prostate cancer (PCa) is the second most frequent cancer in men worldwide. NF-κB seems to play a key role in cell survival, proliferation and invasion, sustaining the heterogeneous multifocal nature of PCa. In recent years, the Hedgehog (Hh) signaling pathway has attracted attention as a therapeutic...

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Bibliographic Details
Main Authors: Davide Vecchiotti, Daniela Verzella, Mauro Di Vito Nolfi, Daniel D’Andrea, Irene Flati, Barbara Di Francesco, Jessica Cornice, Edoardo Alesse, Daria Capece, Francesca Zazzeroni
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Cells
Subjects:
prostate cancer
NF-κB
Sonic Hedgehog
GLI1
Online Access:https://www.mdpi.com/2073-4409/11/13/2118

Internet

https://www.mdpi.com/2073-4409/11/13/2118

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