Role of TLR4 Receptor Complex in the Regulation of the Innate Immune Response by Fibronectin

Chronic inflammation and subsequent tissue fibrosis are associated with a biochemical and mechanical remodeling of the fibronectin matrix. Due to its conformational lability, fibronectin is considerably stretched by the contractile forces of the fibrotic microenvironment, resulting in the unfolding...

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Bibliographic Details
Main Authors: Mingzhe Zheng, Anthony Ambesi, Paula J. McKeown-Longo
Format: Article
Language:English
Published: MDPI AG 2020-01-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/9/1/216