Exploiting gene dependency to inform drug development for multiple myeloma

Abstract Despite recent advances in therapy, multiple myeloma essentially remains an incurable malignancy. Targeting tumour-specific essential genes, which constitute a druggable dependency, potentially offers a strategy for developing new therapeutic agents to treat MM and overcome drug resistance....

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Bibliographic Details
Main Authors: Molly Went, Phuc H. Hoang, Philip J. Law, Martin F. Kaiser, Richard S. Houlston
Format: Article
Language:English
Published: Nature Portfolio 2022-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-16940-7