Distinct Role of Mono-2-ethylhexyl Phthalate in Neuronal Transmission in Rat CA3 Hippocampal Neurons: Involvement of Ion Channels

Distinct Role of Mono-2-ethylhexyl Phthalate in Neuronal Transmission in Rat CA3 Hippocampal Neurons: Involvement of Ion Channels

Mono-(2-ethylhexyl) phthalate (MEHP) is one of the main active metabolites of di-(2-ethylhexyl) phthalate (DEHP). In our previous works, by using rat and Drosophila models, we showed a disruption of neural function due to DEHP. However, the exact neural effects of MEHP are still unclear. To explore...

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Bibliographic Details
Main Authors: Yi Lu, Hong Wang, Junqing Yang, Wengao Jiang, Hong Xin, Ying Luo, Santiago Loya-López, Huaiyu Gu, Dongzhi Ran
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Molecules
Subjects:
Mono-2-ethylhexyl phthalate
neuronal transmission
hippocampal neurons
ion channels
neural excitability
synaptic plasticity
Online Access:https://www.mdpi.com/1420-3049/27/10/3082

Internet

https://www.mdpi.com/1420-3049/27/10/3082

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