Antidepressant duloxetine hydrochloride protects against ovariectomy-induced bone loss in mice by inhibiting osteoclast differentiation

Antidepressant duloxetine hydrochloride protects against ovariectomy-induced bone loss in mice by inhibiting osteoclast differentiation

Background: Several studies have reported the association between osteoporosis and major depressive disorder (MDD) as well as the use of antidepressants. However, it remains to be elucidated whether these associations are related to exposure to antidepressants, a consequence of a disease process, or...

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Bibliographic Details
Main Authors: Weijun Zhou, Wenyun Zhou, Yonghao Bi, Zibin Zhou, Zhigao Zhou, Shaozhe Chen, Gang Xie, Zhen Lian, Guixin Yuan, Guanfeng Yao
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Duloxetine hydrochloride
Major depressive disorder
Osteoclasts
RNA-Seq
ERK
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332223016086

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http://www.sciencedirect.com/science/article/pii/S0753332223016086

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