Improvement of microcirculatory impairment in patients with predialysis chronic kidney disease after AST-120 administration

Abstract Background Endothelial dysfunction starts at an earlier stage in patients with chronic kidney disease (CKD), and induces macro- and microcirculatory impairments. We evaluated whether uremic toxin-lowering therapy could improve endothelial function in patients with CKD. Methods We performed...

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Bibliographic Details
Main Authors: Takayasu Ohtake, Yasuhiro Mochida, Kunihiro Ishioka, Hidekazu Moriya, Sumi Hidaka, Masahiro Hirata, Hirokazu Yamada, Hiromichi Kumagai, Shuzo Kobayashi
Format: Article
Language:English
Published: BMC 2020-06-01
Series:Renal Replacement Therapy
Subjects:
Online Access:http://link.springer.com/article/10.1186/s41100-020-00276-x