Oncogene-mediated metabolic gene signature predicts breast cancer outcome

Abstract Breast cancer remains the second most lethal cancer among women in the United States and triple-negative breast cancer is the most aggressive subtype with limited treatment options. Trop2, a cell membrane glycoprotein, is overexpressed in almost all epithelial cancers. In this study, we dem...

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Bibliographic Details
Main Authors: Merve Aslan, En-Chi Hsu, Fernando J. Garcia-Marques, Abel Bermudez, Shiqin Liu, Michelle Shen, Meredith West, Chiyuan Amy Zhang, Meghan A. Rice, James D. Brooks, Robert West, Sharon J. Pitteri, Balázs Győrffy, Tanya Stoyanova
Format: Article
Language:English
Published: Nature Portfolio 2021-10-01
Series:npj Breast Cancer
Online Access:https://doi.org/10.1038/s41523-021-00341-6