Liver enzyme abnormalities and associated risk factors in HIV patients on efavirenz-based HAART with or without tuberculosis co-infection in Tanzania.

To investigate the timing, incidence, clinical presentation, pharmacokinetics and pharmacogenetic predictors for antiretroviral and anti-tuberculosis drug induced liver injury (DILI) in HIV patients with or without TB co-infection.A total of 473 treatment naïve HIV patients (253 HIV only and 220 wit...

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Bibliographic Details
Main Authors: Sabina Mugusi, Eliford Ngaimisi, Mohamed Janabi, Omary Minzi, Muhammad Bakari, Klaus-Dieter Riedel, Juergen Burhenne, Lars Lindquist, Ferdinand Mugusi, Eric Sandstrom, Eleni Aklillu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3394799?pdf=render