Complement-membrane regulatory proteins are absent from the nodes of Ranvier in the peripheral nervous system

Abstract Background Homozygous CD59-deficient patients manifest with recurrent peripheral neuropathy resembling Guillain-Barré syndrome (GBS), hemolytic anemia and recurrent strokes. Variable mutations in CD59 leading to loss of function have been described and, overall, 17/18 of patients with any m...

Full description

Bibliographic Details
Main Authors: Netanel Karbian, Yael Eshed-Eisenbach, Marian Zeibak, Adi Tabib, Natasha Sukhanov, Anya Vainshtein, B. Paul Morgan, Yakov Fellig, Elior Peles, Dror Mevorach
Format: Article
Language:English
Published: BMC 2023-10-01
Series:Journal of Neuroinflammation
Subjects:
Online Access:https://doi.org/10.1186/s12974-023-02920-9