The E. coli CNF1 as a Pioneering Therapy for the Central Nervous System Diseases

The E. coli CNF1 as a Pioneering Therapy for the Central Nervous System Diseases

The Cytotoxic Necrotizing Factor 1 (CNF1), a protein toxin from pathogenic E. coli, modulates the Rho GTPases, thus, directing the organization of the actin cytoskeleton. In the nervous system, the Rho GTPases play a key role in several processes, controlling the morphogenesis of dendritic spines a...

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Bibliographic Details
Main Authors: Sara Travaglione, Stefano Loizzo, Giulia Ballan, Carla Fiorentini, Alessia Fabbri
Format: Article
Language:English
Published: MDPI AG 2014-01-01
Series:Toxins
Subjects:
CNF1
actin cytoskeleton
synaptic plasticity
Rho GTPases
Online Access:http://www.mdpi.com/2072-6651/6/1/270

Internet

http://www.mdpi.com/2072-6651/6/1/270

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