STM2457 Inhibits METTL3-Mediated m6A Modification of miR-30c to Alleviate Spinal Cord Injury by Inducing the ATG5-Mediated Autophagy

STM2457 Inhibits METTL3-Mediated m6A Modification of miR-30c to Alleviate Spinal Cord Injury by Inducing the ATG5-Mediated Autophagy

Objective The study aimed to investigate the role of N6-methyladenosine (m6A) modification in spinal cord injury (SCI) and its underlying mechanism, focusing on the interplay between m6A methyltransferase-like 3 (METTL3), miR-30c, and autophagy-related proteins. Methods An SCI model was established...

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Bibliographic Details
Main Authors: Gang Chen, Zhitao Shangguan, Xiaoqing Ye, Zhi Chen, Jiandong Li, Wenge Liu
Format: Article
Language:English
Published: Korean Spinal Neurosurgery Society 2024-09-01
Series:Neurospine
Subjects:
spinal cord injury
m6a modification
mettl3
stm2457
atg5
autophagy
Online Access:http://e-neurospine.org/upload/pdf/ns-2448494-247.pdf

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http://e-neurospine.org/upload/pdf/ns-2448494-247.pdf

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