Pathogenicity and virulence mechanisms of Lassa virus and its animal modeling, diagnostic, prophylactic, and therapeutic developments

Lassa fever (LF) is a deadly viral hemorrhagic disease that is endemic to West Africa. The causative agent of LF is Lassa virus (LASV), which causes approximately 300,000 infections and 5,000 deaths annually. There are currently no approved therapeutics or FDA-approved vaccines against LASV. The hig...

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Bibliographic Details
Main Authors: Hannah L. Murphy, Hinh Ly
Format: Article
Language:English
Published: Taylor & Francis Group 2021-12-01
Series:Virulence
Subjects:
Online Access:http://dx.doi.org/10.1080/21505594.2021.2000290