Caveolin-initiated macropinocytosis is required for efficient silica nanoparticles’ transcytosis across the alveolar epithelial barrier

Caveolin-initiated macropinocytosis is required for efficient silica nanoparticles’ transcytosis across the alveolar epithelial barrier

Abstract Removal of particulate materials that would otherwise cumulate within the airspace and hinder the gas exchange is one of the central processes of maintaining lung homeostasis. While the importance of the particle uptake by alveolar macrophages and their expulsion via the airways mucociliary...

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Bibliographic Details
Main Authors: Pascal Detampel, Sara Tehranian, Priyanka Mukherjee, Morgan Foret, Tobias Fuerstenhaupt, Ali Darbandi, Nawaf Bogari, Magda Hlasny, Ayodeji Jeje, Michal A. Olszewski, Anutosh Ganguly, Matthias Amrein
Format: Article
Language:English
Published: Nature Portfolio 2022-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-13388-7

Internet

https://doi.org/10.1038/s41598-022-13388-7

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